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The sensing element consists of the internal elements of a webcam, a 12-mm f/1.2 CCTV lens, two green emission filters, and a computer to collect and analyze data. The sample handling module consists of a flow cell and a programmable syringe pump.

() Schematic of a cell (i) traversing a number of pixels equal to its length plus one pixel, showing (ii) a maximum brightness achieved in the pixel at the image center.

Optical detection technologies used for many types of biological and clinical analysis can play a significant role in addressing this need, but must be sufficiently affordable and portable for use in global health settings.

Most current clinical optical imaging technologies are accurate and sensitive, but also expensive and difficult to adapt for use in these settings.

However, the relatively low sensitivities of these devices limit their clinical utility.